The end of animal testing? In vitro testing.

Your skin is a critically important organ. It’s also very sensitive. So how do the makers of skin care products ensure they aren’t inadvertently damaging the skin of their customers each time they introduce a new formulation? 

For many years, the answer has been to test chemicals on animals before they are released for sale to humans. Yet animal testing is a controversial process that many find repugnant. 

That’s why it’s good to learn of a new skin sensitization test that could do away with clinical trials on animals. Kao and Shiseido have developed a technique that enables substances to be tested in vitro, using human immune cells. 

The human Cell Line Activation Test (h-CLAT) is described in an OECD paper and further explained in this news story

h-CLAT" is an alternative method for evaluating the skin sensitization to chemicals in an accurate and prompt manner with lower cost based on the system in which two types of proteins (CD86*3 and CD54*4 ) increase on the cell surface of the human acute monocytic leukemia cell line, THP-1.

With Europe prohibiting all animal testing for cosmetic products, we can expect further development of sophisticated in-vitro tests to ensure the safety of skin care products.

Leave a comment

Please note, comments must be approved before they are published

RESTORE SKIN TO ITS NATIVE STATE OF HEALTH

MEET THE DOCTOR

"Skincare science needs to be on the very edge of social change and evolution in order to succeed."

Dr. Mark Gray

TRY BEAUTY FROM THE BRINK

SEE THE DETAIL